Pain management often involves oral pain medications, but this can come with many side effects.  The use of topical agents can help avoid systemic side effects while still being successful in managing pain. Cutaneous analgesia after transdermal application of amitriptyline versus lidocaine in rats.
https://www.ncbi.nlm.nih.gov/pubmed?term=12761001

Topical amitriptyline in healthy volunteers.
https://www.ncbi.nlm.nih.gov/pubmed?term=12945021

Topical analgesics.
https://www.ncbi.nlm.nih.gov/pubmed?term=22440379

Local application of strong opioids and wound-related pain.
https://www.ncbi.nlm.nih.gov/pubmed?term=22216634 

Characterization of the antihyperalgesic action of a novel peripheral mu-opioid receptor agonist–loperamide.
https://www.ncbi.nlm.nih.gov/pubmed?term=9915332

This condition that causes excessive can be harmful psychologically and social for the person it affects. This could be an especially harmful problem with athletes. Topical treatments are the most common treatment and compounded possibilities include aluminum chloride solutions or topical methenamine.

Comparison of topical methenamine, glutaraldehyde and tap water Iontophoresis for palmoplantar hyperhidrosis.https://www.ncbi.nlm.nih.gov/pubmed?term=20953017

Treatment options for hyperhidrosis
https://www.ncbi.nlm.nih.gov/pubmed?term=21714579

NSAIDs are some of the most commonly prescribed pain and anti-inflammatory drugs, but they can have serious side effects especially for the gastro-intestinal system.  Compounded topical application of these same drugs can prove to be as beneficial as when taken orally without the complications of systemic side effects.Topical Nonsteroidal Anti-Inflammatory Drugs: The Importance of Drug, Delivery, and Therapeutic Outcome.
https://www.ncbi.nlm.nih.gov/pubmed?term=22367354

Coming to terms with nonsteroidal anti-inflammatory drug gastropathy.
https://www.ncbi.nlm.nih.gov/pubmed?term=22564130

Evolution of Topical NSAIDs in the Guidelines for Treatment of Osteoarthritis in Elderly Patients.
https://www.ncbi.nlm.nih.gov/pubmed?term=22559274

Quantitative systematic review of topically applied non-steroidal anti-inflammatory drugs.
https://www.ncbi.nlm.nih.gov/pubmed?term=9487165

Plantar fasciitis can be very painful and sometimes debilitating.  Treatments often take several weeks if not longer to see results and usually require a reduction in activity.  Athletes especially often want faster results for this condition and new opportunities with iontophoresis and compounded topical medications may achieve that. Treatment of plantar fasciitis by iontophoresis of 0.4% dexamethasone. A randomized, double-blind, placebo-controlled study.
https://www.ncbi.nlm.nih.gov/pubmed?term=9167809