Reversing and preventing the visible aging of skin is a major concern for many adults. These signs can be from normal aging or excessive sun exposure. Regardless of the cause compounded treatments can offer treatments not found elsewhere. Treatment of skin aging with topical estrogens.
https://www.ncbi.nlm.nih.gov/pubmed?term=8876303
Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin.
https://www.ncbi.nlm.nih.gov/pubmed?term=14616378