Treatments for nausea and vomiting can include some oral medications, rectal suppositories, and IV combinations. Through compounding new routes of administration or combinations can be made, including transdermal and intranasal routes. 

Intranasal metoclopramide. 

Nasal absorption of ondansetron in rats: an alternative route of drug delivery.

Bioavailability of Promethazine in a Topical Pluronic Lecithin Organogel: A Pilot Study